Dog Sedative For Grooming. Gabapentin is a medication that can be used for several purposes, including seizure control, anxiety relief, sedation, and pain management. In severe cases where a dog is completely restless and hyperactive, general anesthesia can be used as a sedative for dogs.

Trazodone can both sedate a dog and relieve anxiety. It does have sedating side effects. To avoid this stress on their dog, many people turn to dog tranquilizer pills as a dog sedative for grooming.